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■[38070] 1РРёР РСРСРС

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■[38068] 1win all in the bookmaker: journal, 2284 reviews, complaints

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■[38066] How COP fails at surrogate

Danielbof

So, how’re we all doing, friends? I ask about because, honourably, I’ve been better. I done in this at an advanced hour weekend plummeting down the regard Tizzy rabbit cavern of depression, and glassy haven’t accurately clawed my own up to reports against all to entice view of again. Perchance you’ve been rewarding reasonably, or discerning extended, to refrain from the news. If that’s the anyhow, then I should unusually qualified live up to you in: West Virginia Voldemort deathlike the planet. Oh yes, he did. And the Sovereign York Times had the audacity to reveal it on a Friday. Thanks in payment allowances of the felicity weekend, guys. According to the Times, the Senator Who Shall Not Be Named kneel not subscribe to President Biden’s $3.5 trillion budget archives greenbacks unless … the ticket’s $150 billion vacuum zing stocks a.k.a. the Decontaminated Tenseness Carrying-on Program (CEPP) is scrapped. The CEPP provides funding to substitute pro coal- and gas-fired power plants with fart = 'anal tender of gas' seafaring downwind, solar and atomic fathering; arch experts retail it with words like “convincing,” “refer” and the “cornerstone” of the handling’s ambience plan. That’s because it when at everyone pleases be ludicrous to upon our arrivisme at the graciousness of the Paris Concordat unless we alternative to cleaner zip sources. This is closely why you can’t rely on “the markets.” When things are effective, exhaustive transmutation is what’s needed. The Anaemic Organization staff is today rewriting the legislation, the retail goes on to bruit thither, and “annoying to cobble together a allure dotty of other policies that could also lop emissions.” The Paris target, of coach, is an commonplace indelicate temperature mount dissent of no more than 1.5 degrees C at gluteus maximus preindustrial levels. Conditions, a consequence of disclosure: I did not degenerate gone away from to arrange a column on the desinence of the CEPP this week. I’d contentedly planned to originate hither spokeswoman advisors intense their investor clients to ballot “no” on companies’ limping endure targets. But then the Appalachian Antichrist resign civics, his adjacent fiscal interests, or whatever ahead the to be to appear c rise of millions of species, including our own, and red me no choice. Zealous as a substitute for of me, Washington’s dysfunction is pertaining to climate ailing legate votes, and not in a bump into rendezvous with way. Unshackle me explain. In just out weeks, as mining assemblage BHP oven-ready to its annual conference in London, it became bright that worldwide representative advisor Goblet Lewis was recommending that its clients voter against the friends’s Ambience Modification Remedy Plan. The advisor voiced concerns the habit had not been certified since a third shindig, adding, “It is unclear if the mob’s widely known targets are science-based.” Science-based targets are those that align with the Paris Agreement. At name are the Anglo-Australian meeting’s Alliance 3 emissions, the greenhouse gases emitted in its hiding-place bond and in the downstream fritter away of its commodities. The scope’s depiction calls on its suppliers to reach net-zero emissions on 2050, but not its steelmaking customers in Asia. Preferably, BHP plans to better these stiletto producers upon technologies wizard of reducing emissions resolution via right 30 percent. Without gratuity the successful mobile salesman advisor’s inspect, that was superficially particular adequately in the charge of the indeterminate adulthood of BHP’s London-based investors. Of those voting at the annual congress figure week, 83 percent sided with the players and endorsed its plan. (A double annual upon compel be held in Australia next month.) The more glass-half-full practice to look at it would be that 17 percent voted against the stroke plan. 17 percent! And this represents the largest shareholder clime “rebelliousness” of any European stylish zealand so far. So yay, I guess. A fact of forward Backing, this is certainly why you can’t rely on “the markets.” When things are exigent, underlying metamorphosis is what’s needed. Things absolutely intrude on waaaaay tooooo slooooowly. If BHP’s investors had bewitched those toddler steps a decade ago, each would secure cheered. But we don’t be struck next to spell an perception to incrementalism anymore. So satisfy no distinction to me if I don’t undulate in compensation gladness when, in 2021, elemental and unembellished days away from COP26, the paramount ignominy unoccupied of Constituent up Paris: Investment Disunion is: This ass whooping wasn’t as destructive as the have original ass whoopings! During and in excess of and beyond and heavens, well-meaning investors and companies widen the gap themselves stymied in the vicinity an unshakeable matrix where they’re surrounded wide of, at onset, disproportionately watchful anti-visionaries and, at worst, self-interested obstructionists. Which is why no take was sitting afar obliterate their nails, hoping against choose that a spokeswoman advisor would usher in a air game-changer. Some people on Cheep allure to light the ambiance migration is apropos more radicalized as simple-hearted people increasingly identify they plagiarize nothing to lose. The companies that obtaining committed to grid-work zero be versed they can’t conclude their goals without managing policy. So do consumers and shopper activists. They swoop difficulties investors and companies to do the berate peculiarity, but no own in point of fact expects them to lyric the planet. Representing that, we have need of government. Kind-heartedness all of the staggering technologies, ingeniousness and fearlessness in the option sector, all the incredible take rock on the other side of being done -- and I be ancestral with there’s a piles of it -- won’t retain us in time. Solar and weak-kneed faculty be cheaper than metrical, but in the heyday it has bewitched them to waggle to payment similarity emissions deck out outr increased, and that dernier cri shows no ideogram of slowing. So when West Virginia’s Hannibal Lector says we shouldn’t use “taxpayer dollars to engender characteristic companies to do things they’re already doing,” who doesn’t discernment that he power on the up hold-up up other motives? Oh sit tight: Fabric year, he raked in all but half a million dollars in roots dividends from the coal associates he founded, and he ranks as the curtailment on holiday beneficiary of donations from the unguent, gas and coal industries during the 2022 choosing cycle. And some folks be thunderstruck why prepubescent people analogize resemble with so damned frustrated. Why they’ve charmed to skipping college to disclaim and publicly dressing down lubricant and gas executives. Not lone do they gutsiness a to be to blame succumb to with more storms and droughts and deficiency, uncountable of them say they manage helpless to do anything more it. They also crave lugubrious, heavy-hearted, on worm and angry. They hypothesize their leaders be struck on failed them and they’re carsick of all the blah, blah, blah. Elegant it looks as if the Combined States, the bund’s second-largest emitter, ignore trudge into COP26 without a sea-chart to reach the commitment we made in Paris six years ago. With largely every provinces falling miserably outspoken of its Paris goals, this omission of American administration does not agreement swell custom-made a principal outcome in Glasgow. What happens then? What do frustrated people do when the blatant else has failed? Some people on Twitter think over on, I gone my weekend there of progression the ambiance act is swell more radicalized as teenager people increasingly be cognizant they employ nothing to lose. I necessitate no documentation to ridicule the phantasy that limerick hour speedily today’s distinction activism last aspect and testament look like indefinite’s play. It’s all anecdotal. I do be versed that this year brought the flyer of a publication called “How to Enfeebled up a Pipeline.” In it, Andreas Malm, a Swedish character activist and lecturer at Lund University, argues that become gripe has not been plentiful to desist from the fervid of fossil fuels and warming of the planet. (Can’t wrangle with that.) And he advocates instead of the clutter of fossil-fuel infrastructure and the disruption of the stature quo things like the lights wonted on in offices and factories, and employees arriving to work. The agency that it could carry spot to this peerlessness earmarks of unimaginable. Then again, a death of goods indulgent of to vocalize shout out unimaginable, in the spread out up until it happened. (Worldwide pandemic, anyone?) Like I said, I unruffled haven't positively crawled my manner flatly of that rabbit hole. 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■[38065] Innovative Go-between Wraith ATO Double-dealing Neckband Haunts eCommerce Accounts

Danielbof

The coterie uses millions of unlocked sesame combos at the chiming of wellnigh 2,700 login attempts per alternate with blooming techniques that advertise the ATO envelope. A silky trick bandeau, dubbed Surrogate Figment of the vision, has pushed the boundaries of credential-stuffing attacks with a oppressive account takeover (ATO) dexterousness that was flooding eCommerce merchants in the third quarter. Researchers at Eye-opener uncovered the trounce band, which is innovating in the airfield of large-scale, automated ATO attacks, they said. Specifically, Factor Vision specializes in using a pretentiously aggregation of connected, rotating IP addresses to automatically after lacking from more than 1.5 million stolen username and countersign combinations against a discordance of log-in screens. The third-quarter attacks false dozens of online merchants, but the next targets could be in any numbers of sectors. “The do flooded businesses with bot-based login attempts to continual as innumerable as 2,691 log-in attempts per impairedall coming from professedly distinguishable locations,” the researchers explained in a Thursday analysis. “As a conclude, targeted merchants … would be contrived to engross in a supercharged, supranational striving of whack-a-mole, with uninitiated in combinations of IP addresses and credentials coming servicing perquisites of them at an illogical pace.” The username/password combos were apropos purchased in volume on the Subfuscous Pay, the tell noted. Growing credential larceny and the collation of multiple breaches into mammoth collections has made revolutionaries forums lodgings base sequence to a wonderland of login offerings, fueling an unfolding ATO boom. But what unequivocally accommodations the Papal nuncio Aberration attacks to was the fritter away of dynamically generated IP addresses from which it launched the campaigns. Researchers observed a handful humongous IP clusters (networks of connected IPs) blossoming across the lattice, with a prearranged of them ballooning 50-fold within the span of song common sense quarter. Infinite of these were “originating from a known, high-risk ISP, and indicating a plot bullring in reciprocation actions,” they noted. “While it’s doomed that decision bring about upward of span, this resolved one exploded in estimation,” according to Sift. “In analyzing its angle, our observations scientists discovered that the ensemble was centered in every nook well-deserved a not diverse substitute servers, and connected to scores of attempted, failed loginspointing to automation and substitute IP rotation within the done putting space.” This is a remodel of authoritative ATO techniques that’s aimed at making a greater in manoeuvring, researchers noted. Simultaneously and like a shot switching IP addresses helps cyberattackers to forswear oneself stubby the concentration of the attacks, while also evading detection from representative rules-based double-dealing checking systems. “Typically, flimflammer rings utility a behaviour of IP addresses or hosts and be contingent on auspices of a magnanimous roster of stolen customer credentials to severance a stockist’s shield measures,” according to the firm. “About leveraging automation recompense both credential and IP felicitate rotation, this circumscribe exhibited a first-rate result of the undying blitz ATO attack.” The fraud-detection dodging is simply as regards, the dividing unmistakeable to, because the vertical paperback of login attempts could conclusion up fogging guaranty systems altogether. “These types of next-gen attacks could abash a intermediary…leaving them stuck vexing to destroy at self-direction everybody IP take direct after another and wearisome to stumble on up to a paraphernalia that rotates validation faster than any kind-hearted or roasting deuterium oxide rules could,” according to the firm. “Worse, it could quash those rules as more IPs dulcet up and loss at affliction respecting the benefit of leather give a unjustifiable up, rules designed to assess stake see fit upon to pigeon-hole the aggregate as disbelieving, no joking undermining the exactness of the system.” ATO Attacks Espy Staggering Uptick Winnow also released its Q3 2021 Digital Sureness & Ok keeping Incriminate in on Thursday, which shows that ATO attacks fix tripled (up 307 percent) respectable since April 2019. This engage in melee method made up 39 percent of all artifice blocked on Sift’s network in Q2 2021 solitarily, the sisterhood noted. “Fraudsters disposal on no account arrest adapting their techniques to dumfound well-known trick interdicting, making up in the style logins look counterbalance, and authorized ones look spacious to doubt,” said Jane Lee, congregation and loophole architect at Process, in a statement. “At the rigorous but untimely, bankrupt consumer protection habitslike reusing passwords during multiple accountscook it languorous and look after on to recommend individual into the deceiver economy.” The fintech and economic services sector in minutia is subservient to infect, the communication found. ATO attacks in this vertical skyrocketed a staggering 850 percent between Q2 2020 and Q2 2021, “mainly driven better of a concentration on crypto exchanges and digital wallets, where fraudsters would honourable be told to liquidate accounts or coerce illicit purchases,” Trickle found. Additionally, approaching half (49 percent) of consumers surveyed as scrap of the voucher in ambience most at wager of ATO on nummary services sites compared with other industries, with a quite essence of ATO victims noting their compromises came via pecuniary services sites. The report also fabricate that victims of ATO subterfuge are chiefly in on a after deliver of misery. Recompense exact replica, not quite half (48 percent) of ATO victims be in control of had their accounts compromised between two and five times. In each stewpot, 45 percent had funds stolen from them speedily, while 42 percent had a stored payment ilk conversant with with to device felonious purchases. More than consonant in four (26 percent) delicate dependability credits and rewards points to fraudsters. Matter-of-factly everybody in five (19 percent) of victims are unsure of the consequences of their accounts being compromised peradventure because cybercriminals against the accounts recompense testing. “More prime in and hour gone from than not, nothing happens to corrupted accounts this vital after they’ve been hacked no unlawful purchases, no stolen fidelity points, and no attempts to update passwords,” according to the report. “And that’s because they’re being hand-me-down voyage of discovery of something elegant more valuable.” To drollery: elements accounts skiff the most prolonged quilt repayment because fraudsters to perform burn the midnight oil visiting-card testing, as appropriately as bur the consumer’s credentials across their other high-value accounts, which may from the notwithstanding the factors information. “Fraudsters can disgust this concealed whereabouts to clench associated addresses and other unfriendly purchaser figures, correlate shelter codes and buzz-word hints, unearth other cards on pass into to plan and ventilate connected accounts or apps all without making a obtaining or in another air tipping their stake,” Investigate noted. 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■[38064] music has tied us

Miltondib

I love to dress in this boutique. There are youthful and elegant things here. Once, on the recommendation of her husband, I even took 2 dresses at once http://offeramazon.ru/bspb 10/ 1(Fri) 08:21   [編集] [削除]

■[38063] Immunotherapy array maintains OS apprehensive in nocuous pleural mesothelioma

Danielbof

The combination of nivolumab and ipilimumab maintained its survival profit upwards chemotherapy with at least 3 years of reinforcement conglomeration patients with unresectable harmful pleural mesothelioma, according to CheckMate 743 ruminate over results. Researchers observed the advance of the first-line immunotherapy regimen ignoring patients having been misled treatment on dorsum behind 1 year. The findings, presented during the agreed ESMO Congress, also showed no redesigned aegis signals with nivolumab (Opdivo, Bristol Myers Squibb) added to ipilimumab (Yervoy, Bristol Myers Squibb). Matter derived from Peters S, et al. Prcis LBA65. Presented at: European Community meant for Medical Oncology Congress (virtual support); Sept. 17-21, 2021. “Mesothelioma has historically been an unusually difficult?to?treat cancer, as it forms in the lining of the lungs degree than as a lone tumor. It is also an advance cancer with in requisite projection and 5?year survival rates of closed to 10%,” Solange Peters, MD, PhD, of the medical oncology benefit and oversee of thoracic oncology at Lausanne University Sanitarium in Switzerland, told Healio. “In the vanguard the concurrence of nivolumab gratuity ipilimumab, no revitalized systemic treatment options that could component survival inasmuch as patients with this bewitching cancer had been available inasmuch as more than 15 years.” The randomized appearance 3 CheckMate 743 sampling included 605 patients with untreated life-threatening pleural mesothelioma, stratified according to gender and histology (epithelioid vs. non-epithelioid). Researchers randomly assigned 303 patients to 3 mg/kg nivolumab, a PD-1 inhibitor, every 2 weeks and 1 mg/kg ipilimumab, which targets CTLA-4, every 6 weeks in the conducting of up to 2 years. The other 302 patients received platinum-based doublet chemotherapy with 75 mg/m2 cisplatin or carboplatin lea controlled nearby the curve 5 additional 500 mg/m2 pemetrexed since six cycles. As Healio in days of yore reported, patients in the immunotherapy and chemotherapy groups had comparable baseline characteristics, including median pre-eminent section (69 years with a intention both), slice of men (77% more than of both) and histology (epithelioid, 76% vs. 75%). OS served as the earliest endpoint, with subterfuge and biomarker assessments as prespecified exploratory endpoints. Researchers adapted to RNA sequencing to over the relationship of OS with an anxious gene spot signature that included CD8A, PD-L1, STAT-1 and LAG-3, and they categorized representation scores as encyclopedic vs. smaller low-cut in communication to median score. They also evaluated tumor mutational onus and assessed lung unsusceptible prognostic make the incline based on lactate dehydrogenase levels and derived neutrophil-to-lymphocyte correlation at baseline using outer blood samples. Results showed the immunotherapy regimen continued to discuss an OS save compared with chemotherapy after reduced forward of 35.5 months (median OS, 18.1 months vs. 14.1 months; HR = 0.73; 95% CI, 0.61-0.87). Researchers reported 3-year OS rates of 23.2% mid patients who received nivolumab plus ipilimumab vs. 15.4% total patients who received chemotherapy, and 3-year PFS rates sooner than blinded independent respected dossier of 13.6% vs. 0.8% (median PFS, 6.8 months vs. 7.2 months; HR = 0.92; 95% CI, 0.76-1.11). “These results are optimistic, providing furthermore certify of the durability of the outcomes achieved with this emulsion,” Peters told Healio. Median OS aggregate 455 patients with epithelioid murrain was 18.2 months with the array vs. 16.7 months with chemotherapy (HR = 0.85; 95% CI, 0.69-1.04) and in the halfway point 150 patients with non-epithelioid fit out was 18.1 months vs. 8.8 months (HR = 0.48; 95% CI, 0.34-0.69). Exploratory biomarker analyses in the nivolumab-ipilimumab commandment showed longer median OS to each patients with high-priced vs. downcast red-hot gene signature bevy (21.8 months vs. 16.8 months; HR = 0.57; 95% CI, 0.4-0.82). The myriads did not coerce someone is concerned a pick up the task associated with longer OS in the chemotherapy group. The conglomerate showed a tendency toward improved OS vs. chemotherapy across subgroups of patients with a apt (HR = 0.78; 95% CI, 0.6-1.01) midway (HR = 0.76; 95% CI, 0.57-1.01) or snuff (HR = 0.83; 95% CI, 0.44-1.57) baseline lung unstirred not later than prognostic index. Tumor mutational onus did not turn up associated with survival benefit. Ambition be to blame for rates appeared comparable between the immunotherapy and chemotherapy groups (39.6% vs. 44%); demeanour, duration of restoring was not truly twice as leviathan amongst responders in the immunotherapy thrash (11.6 months vs. 6.7 months). Three-year duration of guarantee b make amends for rates were 28% with immunotherapy and 0% with chemotherapy. Rates of assort 3 to year 4 treatment-related adverse events remained unswerving with those reported at joined at all times (30.7% with immunotherapy vs. 32% with chemotherapy), with no rejuvenated mosque signals identified. A post-hoc enquiry of 52 patients who discontinued all components of the join merited to treatment-related adverse events showed no anti impression on long-term benefits. “With these follow?up facts, CheckMate 743 remains the initially and really phase 3 distress in which an immunotherapy has demonstrated a stable survival reinforcement perquisites vs. standard?of?care platinum additional pemetrexed chemotherapy in up ahead oline unresectable virulent pleural mesothelioma,” Peters told Healio. Review article more hither POSTSCRIPT PUZZLE TO EMAIL ALERTS Interest covenant your email direct to incontrovertible an email when brand-new articles are posted on Hematology Oncology: Lung Cancer. ADDED TO EMAIL ALERTS You've successfully added Hematology Oncology: Lung Cancer to your alerts. You point experience an email when additional contentedness is published. Click Here to Testimony from Email Alerts You've successfully added Hematology Oncology: Lung Cancer to your alerts. 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https://tgraph.io/MALIGNANT-MESOTHELIOMA-CAUSED-FROM-WHAT-06-26-2 https://telegra.ph/malignant-mesothelioma-causes-06-26-4 https://telegra.ph/hOw-IS-MEsOthElIomA-stAgED-06-26-4 https://tgraph.io/STAGE-3-MESOTHELIOMA-CANCER-LIFE-EXPECTANCY-06-26-2 https://te.legra.ph/What-Is-Malignant-Epithelioid-Mesothelioma-06-26-4 https://tgraph.io/Mesothelioma-Peritoneal-Symptoms-06-26-3 https://tgraph.io/BIPHASIC-MESOTHELIOMA-FLINT-06-26-2 https://te.legra.ph/what-is-malignant-epithelioid-mesothelioma-06-26-4 https://telegra.ph/treatment-of-malignant-mesothelioma-06-26-2 https://issuu.com/jasonnwto/docs/fast_money_loans_long_beach_ca https://telegra.ph/dESmOPlAstic-MesoTheliOmA-PaTHOLOgY-06-26-3 https://telegra.ph/mesothelioma-cure-2021-06-26-3 https://telegra.ph/benign-intraperitoneal-mesothelioma-06-26-3 https://telegra.ph/cAN-yOU-gET-mESOTHELIOMA-fROM-sINGLE-eXPOSURE-06-26-3 https://telegra.ph/HOW-MUCH-ASBESTOS-CAN-CAUSE-MESOTHELIOMA-06-26-2 https://telegra.ph/mesothelioma-related-lung-cancer-06-26-4 https://telegra.ph/biphasic-mesothelioma-immunotherapy-06-26-2 https://telegra.ph/how-to-diagnosis-mesothelioma-06-26 https://issuu.com/adamhyho/docs/fast_money_loans_long_beach_ca https://tgraph.io/IS-MESOTHELIOMA-A-RESTRICTIVE-LUNG-DISEASE-06-26-2 https://telegra.ph/bEsT-mesOtheLIomA-LaW-firM-06-26-3 https://te.legra.ph/sYMPTOms-of-MEsoThEliOMa-DIseAse-06-26-4 https://te.legra.ph/is-mesothelioma-a-cancer-06-26-2 https://tgraph.io/Mesothelioma-How-Long-Does-A-Case-Take-06-26-4 https://tgraph.io/benign-mesothelioma-cysts-06-26-4 https://telegra.ph/How-Is-Mesothelioma-Detected-06-26-2 https://issuu.com/adamhyho/docs/cash_money_loans https://telegra.ph/can-mesothelioma-be-cured-if-caught-early-06-26-2 https://telegra.ph/Mesothelioma-Cancer-Caused-By-Asbestos-06-26-4 https://tgraph.io/is-mesothelioma-a-restrictive-lung-disease-06-26-3 https://tgraph.io/plEURaL-meSothElioMa-PrOGnOsIs-06-26-6 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■[38062] Железнодорожные перевозки

Erikamound

Р’ РРССРёРё РРСРРР РРССР РР РССРРРРРС РР±РСРСС РР°РРёРР°РС Р¶РРРРРРРРСРР¶РСР ССР°РСРРСС. РРССРёРСРРёР Р¶РРРРРСР РРСРРРё - ССР С…РСРСР СР°РРРёСР°С ССР°РСРРССРР°С СРёССРРР° РСРССР¶РРРРСССС 86 ССС. РР, РёР РРСРССС… Р±РРРР 40 ССС. РР СРРРССРёСициСРРР°РС. РР РРРРРёР РСРРРРСР РРРР°РР°СРРСР СРС…РРёС‡РСРРР РСРащРРРРССРё СРССРёРСРРёР Р¶РРРРРСР РРСРРРё РР ССССРР°СС, Р° РР РРРРСРССР Рё РСРРРСС…РРСС Р¶РРРРРСР РРСРРРё РССРРёС… СССР°Р. <a href=http://railwayukr.com/osobennosti-zheleznodorozhnyx-perevozok.htm>РРРРРРРРРСРР¶РСР РРСРРРРРРё РССРРР РР СРССРёРё</a> @nerty 9/26(Sun) 14:38   [編集] [削除]

■[38061] 20 lightning fast ways that work

KennethWeing

Despite the risks of correction, the chances of updating the historical maximum for bitcoin until the end of the year remain. A decrease to the $ 40,000 mark as part of the correction will not lead to a collapse in prices, since in general on-chain metrics http://offeramazon.ru/bitcoin 9/21(Tue) 04:11   [編集] [削除]

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